What are some tips on getting an effective ground game going?

Strong OL, top notch RB. Smart playbook. Weak opponent's DL

You don't really need a top notch RB, just a fast one.

This is true. I've got a starter, in another of my leagues, who my ratings put in the low 90s overall. But his backup, rated in the mid-60s is averaging over 4 yards per carry as his backup. His top rating is his speed.

Good oline and a fast RB. Multiple RB's are even better as you can rotate them. Most of all, don't be afraid to run a lot.

That's the true key there.. gotta stay committed!

You can look for traditional passing sets that have run plays. Back in the day the 1-1-3 was used a lot as most base defenses would be nickel and you could exploit the personnel mismatch. Most vets made rules to counter that. You also could override a WR with speed and acc in some goal line toss/outside runs as well as some quick hitting runs to try and use that speed as an advantage. These are what I see most commonly.

Pay attention to which running plays really work and which don't. Giving up totally on your running game is very bad for your defense, which is a Really Bad Thing. Stay committed to running, even if/though it sucks.

Well, a fast and quick back helps . One without butter fingers that drops the rock every time someone says "BOO" helps even more!!!

Is that why I can now beat people up with my slot receiver? It sure is interesting to find out how these things came to be.